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Beilstein J. Org. Chem. 2010, 6, No. 48, doi:10.3762/bjoc.6.48
Graphical Abstract
Scheme 1: Diels–Alder reaction of diene 2 with 4 and 6. aThe other isomers of 7a and 7b were isolated in 8% a...
Scheme 2: Synthetic concept toward multi-substituted gem-difluoroisoquinolinones.
Figure 1: Comparison of coupling constant of vinyl protons.
Scheme 3: Diels–Alder reaction with 9 and 6. aCombined yield of two isomers.